miR-33a, an important marker and putative therapeutic target in chronic HBV-induced fibrosis
نویسندگان
چکیده
1 Department of Occupational and Environmental Health, School of Public Health, Wuhan University, Wuhan 430071, China 2 Department of Basic Medicine, Nanyang Medical College, Nanyang 473003, China 3 Department of Cardiovascular Medicine, The Affiliated Zhongnan Hospital of Wuhan University, Wuhan 430071, China 4 Central Laboratory, The Central Hospital of Wuhan, Tongji Medical College, Huazhong niversity of Science and Technology, Wuhan 430014, China
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MircoRNA-33a inhibits epithelial-to-mesenchymal transition and metastasis and could be a prognostic marker in non-small cell lung cancer
Understanding the molecular mechanism by which epithelial mesenchymal transition (EMT)-mediated cancer metastasis and how microRNA (miRNA) regulates lung cancer progression via Twist1-activated EMT may provide potential therapeutic targets for cancer therapy. Here we found that miR-33a, an intronic miRNA located within the sterol regulatory element-binding protein 2 (SREBP-2) gene, is expressed...
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